But, there are some broad research areas and themes that keep me coming back. I am studying the sensorimotor processes that make perception possible. We're proud to be ranked first for research impact and top 10 for overall research performance in the Times Higher Education ranking of the Research Excellence Framework 2014. Research In addition to looking at the biological effects of the absence of gene activity we are also looking at the effects of tissue-specific expression in otherwise null backgrounds and the biological effects of tissue-specific overexpression in wild type backgrounds. Below – Listen to Dr. Paluzzi speak about his research! Human-induced ecological stressors, such as global climate change, pollution, introduction of non-indigenous species, and alterations in land use, water quality and habitat, are impacting our native ecosystems. My research and writings have focused on the history of genetics, molecular biology, evolutionary biology, symbiosis and horizontal gene transfer in evolution, tropical ecology and biodiversity. To study these processes we a positive-sensed (i.e. Neuroendocrine systems are investigated at the molecular, cellular and tissue level in order to determine their importance and contribution to the biology of whole organism. Dozens of species of North American songbirds have declined significantly over the past four decades, many of which are species that migrate to Central or South America during the northern winter. We have established teaching provision on all our programmes through a mixture of online and in-person methods, with the aim of providing a stimulating, engaging and supportive experience. Entry requirements. The viral processes that we are interested in understanding include: RNA sequences and structures within the ssRNA TBSV genome are involved in each of these processes and we aim to: Electrical Synapses in Health and Disease: From Genes to Systems. 2nd Annual Conference York University Friday, October 18, 2019 VENUE: Life Science Building Lobby and Room 103, York University Registration Fee: $10 charge (paid at registration desk in cash).RSVP required. We are trying to understand what tethers are made of and what they do. In doing so, I am particularly interested in “person perception”, which includes face recognition, biological motion, and other aspects of the appearance and perception of other people. There are two major areas of interest in Dr. Hilliker’s lab: the molecular and genetic analysis of Drosophila heterochromatin; and the molecular genetic analysis of oxygen defense mechanisms in Drosophila. Although I am in the Teaching Stream, I continue to study bird migration. While I investigate questions founded solely within each discipline, I also explore questions that exist in the overlap between the disciplines, using a variety of techniques across numerous biological levels. This focus ensures that within each area there is a critical mass of interacting people and shared resources to produce a strong research environment. However, my research interests are broad, as I am interested in a breadth of paleoecological indicators (including algae (e.g. In addition, results of our research can be used to predict changes in the mosquito and midge species composition by increased environmental salinity from the continued use of road salt. M3J 1P3 mscheid@yorku.ca, Faculty Profile COVID-19 update. Sheykhani et al. Obesity is also a major risk factor for development of heart failure which occurs when the heart is unable to pump sufficient blood to meet the demands of the body. Daphnia and Chaoborus) to examine aquatic ecosystem responses to a variety of human-induced stressors. Research Areas: signaling transduction, physiology, electrophysiology, vascular diseases, smooth muscle cells, endothelial dysfunction, cell proliferation, bioenergetics, insulin resistance, genetic and epigenetic regulation, hydrogen sulfide, gasotransmitters. Sheykhani et al. We employ molecular genetics and neurophysiological technologies to investigate the endocrinology of stress, and the molecular consequences of exposure to environmental stressors (e.g., anthropogenic pollutants, environmental changes). We have studied the mechanisms involved in the defence against ROS. He also collaborates with other faculty members in the department. We welcome applications if you have, or expect to gain, at least an upper second class honours degree, or equivalent, in biosciences. The research interests of faculty span the broad areas of animal physiology, molecular and cellular biology, and ecology and evolution. Representative Publications: The midgut and Malpighian tubules also play a role in maintaining hydromineral balance. Visit their Web sites and faculty profiles to see whether they’re involved with any of YorkU Research Centres and Institutes. Members of this conserved family of RNA chaperones have critical functions in cellular growth. Naturally, research in my York University lab. The lab has three main foci: molecular phylogeny, behavioural ecology, and comparative genomics. My laboratory has made wide ranging contributions to fundamental mechanisms in animal physiology. The focus of the research in our laboratory is to understand, at a molecular level, fundamental processes that are utilized by RNA viruses during their infection of host cells. Informed by a strong commitment to shared values, including the promotion of social justice, diversity, and the public good, we aspire through our research to better understand the human condition and the world around us and to employ the knowledge we gain in the service of society. This research provides fundamental insight into the functioning of these organisms and furthers our knowledge on these medically-important species that have adapted to gorging on vertebrate blood and act as chief vectors of various human and animal diseases. Primarily, we use budding yeast, a popular model organism, as our biological system and our methodologies include a combination of molecular biology, biochemistry, yeast genetics, and genome-scale technologies. Identifying tissue targets regulated by hormonal factors, which involves determining receptor expression profiles, allows the subsequent application of tissue-specific bioassays (muscle contraction assay, epithelial transport assay, etc.) We have been working towards a molecular genetic dissection of the distyly locus in Turnera species which determines both the incompatibility system and the floral dimorphism. Quinlan Lab Website Research Opportunities for Biology Students. Research Vision. Peng Lab Website We have over 60 faculty appointed to our graduate program including many award-winning and internationally recognized researchers. Faculty Profile I have often taught Biology of Sex NATS 1660, and wrote the textbook for that course (University of Toronto Press). We focus on nervous and hormonal control processes because of their central and universal importance to animal organisation. Description: I am most interested in the metabolism and physiological functions of hydrogen sulfide (H2S), a gas molecule produced in a wide array of mammalian cells. We have now cloned, and sequenced a BAC clone corresponding to the recessive haplotype, and have cloned and sequenced a majority of the dominant haplotype. With particular strength in animal physiology, faculty members in the Department of Biology lead well funded and very active research programs utilizing a comparative and integrative approach, ranging from studies at the molecular level right through to whole animal physiological homeostasis. Our research interest concerns the basic regulatory mechanisms involved in cellular differentiation. We have a special interest in the origin and maintenance of social behaviour in bees. Historical data and experimental manipulation of landscape settings allows us to determine the habitat requirements and status of wild bee species to make sustainable land use and conservation recommendations. adonini@yorku.ca. Progress in research is monitored by the Supervisory Committee (usually the super… Please visit the Research Opportunities for Biology Students page. Research Area: Cell Biology This work is essential for the protection of natural resources, but also for the development of sustainable industries such as aquaculture. Research in my lab focuses on the genetics and evolution of plant breeding systems in a Neotropical group of plants in the genus Turnera. The role of hormones and growth factors in regulating ovarian follicle growth and oocyte maturation in zebrafish, The role of growth factors and microRNAs in regulating human placental development and their contribution to the development of preeclampsia, Involvement of cyclin G2 and its regulators in the development of epithelial ovarian cancer, 5’ cap-independent translation of viral proteins, Transcription of viral subgenomic (sg) mRNAs, Determine the structure-function relationship of important RNA elements within the genome, Identify and characterize viral and host proteins that interact with these RNA elements, Determine the molecular mechanisms by which these RNA elements and protein factors mediate different viral processes. I have taught a variety of BIOL and NATS courses since I began at York in 2009. As such, deregulation of protein ubiquitination leads to a vast array of human diseases including cancers, immune disorders and neurodegenerative diseases. Type 2 diabetes is characterized by insulin resistance, the failure of peripheral tissues, including liver, muscle, and adipose tissue, to respond to physiologic doses of insulin, and a relative insufficiency of insulin production from pancreatic beta-cells in response to blood glucose levels. (2007). Christopher is a Professor in Biology at York. How does the environment affect the physiology of the gastrointestinal tract and digestion and why have these responses evolved? The Rehan lab research focus is bee biodiversity and social evolution. The Paluzzi lab’s research program focuses on the biology of blood-feeding arthropods including ticks and mosquitoes. Self-funded research opportunities are available for MSc by Research (1-year research programme), MPhil (2-year research programmes) and PhD (3-year research programme).. cpeng@yorku.ca. We are currently focusing our efforts on six genes: quiver (qvr), a putative neuropeptide; withered (whd), which encodes carnitine palmitoyltransferase I (CPT1), Cu Zn superoxide dismutase (SOD1); manganese superoxide dismutase (SOD2); aconitase; and the Drosophila frataxin homologue. Maintaining whole body homeostasis of ions and trace metals is fundamental to the survival of all organisms. Future Students Currently, I am serving a term as Associate Dean for Student Affairs in the Faculty of Science (2016 to 2019). We implicated actin and myosin in force production using inhibitors (e.g., Sheykhani et al., 2013b), and we identified titin, another muscle protein, in spindles (Fabian et al., 2007); thus the matrix might contain actin, myosin and titin. We have done fieldwork in Scotland, England, Scandinavia, Newfoundland, on Hudson Bay, and throughout Ontario. The information gained from this research can provide fundamental insights for development of lead compounds useful for control or eradication of these disease vectors. Progression of heart failure is now commonly believed to result due to a complex interplay of detrimental effects (remodeling). Virginia. ON Canada Subsequent work explored the mechanisms by which these factors regulate cellular gene expression and differentiation. Cytoskeleton 70: 241-259. In my lab, the BioMotion Lab, we are making heavy use of 3D scanning, motion capture technology and virtual realities. Communication between cells in the nervous system is mediated by chemical and electrical synapses. My long term research examines the behavioural ecology and conservation of birds. Research in the Biology graduate program is focused on several broad areas: molecular and cellular biology; vertebrate, invertebrate and plant physiology; ecology and evolution. Based on their structural similarity, these genes belong to the MADS superfamily of DNA binding proteins that are involved in cell fate specification in many organisms ranging from yeasts to humans. We have been evaluating a suite of traditional and non-traditional statistical approaches to determine which are most appropriate for continuous and binary data. Our research spans the biological sciences - from ecology to biomedicine. The ability of adiponectin and lipocalin-2 to mediate direct effects on the heart may help explain the strong association between obesity and cardiovascular complications, including heart failure. Within the research areas, faculty members work on a diversity of research problems, the range of which can best be seen by consulting the detailed descriptions on the Biology website. Learn about York University Libraries’ current remote and on-site services, including book lockers and study spaces. I am constantly looking for interested graduate students from various backgrounds, including Biology, Psychology, Engineering and Computer Science. Faculty Profile My area of research specialization involves examining the chitinous subfossil remains of midges (Diptera: Chironomidae; “chironomids”) in lake and pond sediments, to generate paleoecological assessments of past aquatic ecosystem changes. I am currently engaged in a collaborative project (University of Manitoba and the Ontario Ministry of Natural Resources & Forestry) using GPS tags to study the migration constraints of a nocturnal bird that breeds in Canada and over-winters in the tropics. Research Opportunities. We employ these three levels of biological integration to study bees at multiple evolutionary scales. 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