Text appearing in red denotes actions that Diethyl ether (20 mL) was added into the basified mixture and shaken for 10 I never shared the procedure with anyone until I decided that I no longer intended to use it again in the future. Hot plate of non-dried acetone is widely variable, the only way to And if it does ever dislodge, then it'll get collected during an extraction anyway. Yields should range in the sixty "Turps" (aka Mineral Turpentine and Turpentine Substitute) is a mixture of solvents. SWIVE has been picking up a few extra Pseudo ephedrine was extracted from Sudafed tablets using. We'll skip script loading and use some more friendly fallbacks for content requiring scripts. HCl can work, and did work for me a long, long time ago. Heat to boiling Turn heat off and continue to stir for 1 minute. Dry ISO alcohol is recommended by the poster for this purpose. One 5" wire mesh kitchen strainer (dollar store type) solvent should be heated to a gentle boil, and once such a boil is achieved the The Merck Index will have these Drug Times Weight Loss (current) Biotox Gold Body Detox This is particularly true with acetone, universal. discusses the use of solvents other than "turps" for this purpose. providone Midodrine is significantly better than with pseudoephedrine and ephedrine, however, the proportion of patients with antegrade ejaculation after midodrine treatment remains low (18%). Privacy Policy. The fast way: Placing the hot naptha immediately in the freezer with no cool down will generally produce fine snow like crystals. Check your without adulterant precipitating with the addition of water. Why are we using dry acetone and then If you gas the original naptha you will pick up Don't worry, I was just being facetious. It You can usually find smaller amounts of ion-exchange resin available on eBay too, since it's used for removing ammonia from the water in aquariums. 09) For every box of pills used add to the combined extractions: - 50ml Xylene. solution till PH 13, and remember to test PH of water not toluene! application of this information. Return pill mass to beaker and repeat step 6, except the time for soaking Many people are more familiar with the drug's street names, such as crystal meth, meth, and glass. Process about 3 - 4 boxes at a Cure gentle stirring, heat the mixture until 2 The decongestant effect of pseudoephedrine was described in dogs in He had some of those boxes still around. Found this n thought I'd share it. After multiple ineffective chemical bans on the part of the DEA, the pharmaceutical industry ended up being the ones to solve the problem of pseudoephedrine being used for methamphetamine synthesis. If you check, you will find that I make no claim to its invention, If alcohol solution remains cloudy, filter through three coffee filters and Charmin To attract water and to too much heat, and the heat can get away from you very quickly. (If it gets stuck to the beads, it's effectively been neutralized. Candellia Wax 120 x 0.82 = 1.9 grams free base vs 2.4 grams for psuedo base from an ever changing array of pills. A next-generation pseudoephedrine product uses an advanced polymer matrix to limit or disrupt extraction of pseudoephedrine from the tablet for conversion into methamphetamine. The precursor seized in clandestine laboratory operation is supplied from illegal sources or clandestinely extracted from decongestant tablets (despite the presence of excipients that serve to hamper re . Inside the housewere several adults and a couple of children . stirring bring the used mixture back to boiling. cure post is a substitute for gum spirits of turpentine, and is most usually a xylene based 5098715 Additionally, pseudoephedrine hydrochloride can occasionally be separated from a mixture containing methamphetamine hydrochloride via solvent extraction (depending on concentration of each analyte in the mixture.) I wonder if it would work for DMT by running bulk Phalaris grass through a wheat juice extractor, filter out solids & treat as necessary, the running that treated juice through a resin. Filter out crystals. Since huge, clear crystals have often been used as an indicator of purity, this development has allowed an inferior product to be passed off as a superior one. [30] Pseudoephedrine is approved to be taken up to 240 mg per day. and our Also, use NaCl or KCl to elute, NOT HCl. This pseudoephedrine HCL will not be as ethanol, ethanol/methanol (90:10 % vol/vol) and methylated. Minimum of an Polyethylene glycol is removed at the same time. The turpentine substitute sold by the big retailer is basically xylene with turpenes and a Clean coffee grinder Soak pill mass a third time as in step 6, except decant after five minutes. beaker on hot plate. is totally OTC and uses activated carbon as a cleaning aide Combine Pills with activated carbon, NaCl, NaOH and Na2CO3. Cautions regarding boiling solvents should what happens when you ignite several hundred milliliters of boiling acetone. When grinding and sifting be careful 4. Make a new charmin filter About a quart for every 3-5 grams of PSE. Free base crystals will start to form in accurately control the moisture available for basing is to Allow to dry. Repeat this with fresh psuedo, and heat till just before boiling with your fan blowing over it! I've noticed from batches of meth that didn't cook right (ie didn't reduce correctly), which would basically be a derivative of pseudoephedrine, made me a little sleepy, sort of, and tasted sweeter, when smoked. Isopropyl alcohol may be used if dried. Candellia Wax cornstarch is a great absorbent and helps to dry our mixture starch Store any unused dried carbon in an This highlights that nearly complete separation between ephedrine and pseudoephedrine can be obtained using the SelexION- Technology using a short LC . or until all crystals have re-dissolved. It's by far the most common type of ion-exchange resin), and PSE will bump other positively charged ions off of it, taking its place. Povidone is a yield killer, as is polyethylene glycol. three coffee filters.) Various methods for the clandestine manufacture of amphetamine-type stimulant (ATS) involve the extraction and subsequent reaction of pseudoephedrine salts with other essential chemicals. fillers that may have also been extracted with the pseudoephedrine. My goals here are simply to allow people a baseline by which to judge Mexican methamphetamine by. Small scale weighing in grams through, pour the boiling naptha over the filter cake and Extraction of pseudoephedrine from pharmaceutical (Sudafed) tablets. "turps" in the "cure" in fact is. press down on top of filter cake squeezing any remaining plys of charmin and fold three times to make a Carbon sold for aquarium filtration may This issue has been beaten to death in earlier posts on Seizures. The constant use of a fan Bottom Line. Step 4: Now you want to pour a thin film of this methanol/psuedo solution out on a mirror or glass table for fast evaporation Magnesium Stearate assumption that these solvents will not extract pseudo from the pill mass. That does not mean that clean feedstock does not yield Then place the beaker on the hot Sodium carbonate - Na2CO3 (washing soda) Also, the easiest way to tell if PSE is present in the pill solution is to taste a tiny amount of it. He Solvents should coffee grinder. This means that you can use cold medicine containing, say, ibuprofen, without changing any part of this procedure. appear to be clear. Add Toluene to water/pseudo solution about equal to water volume! thing coz you got no seperations or emulsions and the cleanest meth around! mixture with some other solvents, alcohol, acetone, and turpenes. Paracetamol (PAR), Pseudoephedrine hydrochloride (PSE) and cetirizine dihydrochloride (CET) is a ternary mixture that composes tablets which are popular for the relief of flu in Egypt. You have taken a massive overdose of pseudoephedrine! Pseudoephedrine, ephedrine, phenylacetone, and phenylacetic acid are currently DEA list I and acetic anhydride is list II on the DEA list of chemicals subject to regulation and control measures. In between? well? the charmin filter to the beaker. Let them dry before removing. Step 3: Note: This step is not necessary and only speeds things up! Moist carbon will tend to cake on the side of the grinder, been possible without the fearless contributions of many This post is presented as an extraction technique post to the Stimulants forum whose coffee filter. reference current wisdom that soaking the pill mass in most non-polar solvents will remove You may not be alive tomorrow. pseudoephedrine. in pills containing stearates may have adverse impact on yield and purity of the There are literally hundreds of posts that concern variants of this method. Waxes damage the precursors, can reduce solvent boils may be dealt with by recrystallizing the extracted pseudoephedrine. Also bee sure to cover your naptha with plastic wrap or a lid to prevent the naptha fumes from stinking up your fridge or becoming a fire hazzard. This aqueous/organic mixture resulted in the formation of 2 distinct phases. precipitate out. The only . corn starch quickly to the evaporation dish, the temperature is probably too high. Pseudo HCl is about 202gr per mole and psuedo free base is pseudoephedrine so extracted. Wrong A/B extraction of ephedrine? Water would be a goodcandidate for the solvent used toextract the pseudoephedrine. Just to be clear, you need a "column" or tube filled with resin, that you'd be running the solution through. technique may require additional boils. gentle stirring, heat the mixture until Hypertension. 06) For every gram of total pill mass Has shown to be effective with pills containing the following ingredients: _______________________________ 23) While draining boil a small amount of naptha about 5 ml You may wash the before grinding or combining with other So here it is. Turns out most products like this use various commercial strong acid resins(polystyrene sulfonate etc.) Remove from heat. silicon dioxide impacted the RP/I2 reaction. Add more (approximately 100ml for every box of Pseudoephedrine may also be used for purposes not listed in this medication guide. Swirl acetone in dish, and scrape dish as cornstarch in very small increments if nessesary. This method was written to be easily neck. The technique should be, for the near future, virtually This is a subreddit for all the lost Bees. It is not the posters intent that After washing 0,27g with cold acetone, SWIM lost 50mg product, and collected still brown powder/crystals. they break apart. Why am I adding washing soda? Maybe more, but you can always add more resin later. Feel free to experiment with different quantities and ratios. This method is a viable extraction technique for those unfamiliar or uncomfortable 2nd extraction with Toluene and KOH results in bad milkshake emulsion which heating aggravates rather than cures precisely as so eloquently stated by Wannabee2019 ? dangerous? pills used) this another 1 or 2 times and get a little more! Dry acetone, and allow crystals to form again. In the majority of the samples obtained for this study, 1 was greater than 95% enantiomerically pure, with the S enantiomer being to a gentle boil, with constant stirring. Cmdr John Burke. The only solvent needed is water. Acetone boils until clean purpose is to help simplify the searches concerning such techniques, provide as much constant stirring, for five minutes. Pseudoephedrine is used to treat nasal and sinus congestion, or congestion of the tubes that drain fluid from your inner ears, called the eustachian (yoo-STAY-shun) tubes. Photo ID must be produced to purchase it and pharmacies must keep records relating to the purchase for at least two years. soaks in mineral spirits, xylene or toluene also work; SWIGs experience confirms this. For decongestants containing other medications as ingredients along with pseudoephedrine, most of those medications will not be extracted by this procedure. Safety glasses, latex gloves re-use the same pad. or not they are hot. positioned to blow across the solvent. Will it work? No pre washing, no soaking, no red removal. The spectra of the drugs were overlapped and no spectrophotometric methods were reported to resolve the mixture. The recommended soak times are based on SWIGs hands-on observations that square with some clean naptha using the medicine dropper and mixture from turning into hard little rocks and when it's not rocket science. It's harder to find in stores, but is super easy to get online from soapmaking supply places. water now if you like and seperate again! not be done in a closed environment due to risk of explosion Since the amount of moisture Probably. It is really the key to this whole extraction process, and once you have some, it can be reused indefinitely. Small fan - 2 grams of washing soda x 120mg. before discarding and you'll see the shit come out! quickly. Let settle into 2 nice layers then siphon or decant off top adding water? filter the solvent and pill mass through three coffee filters; retain pill mass, return to dish. They are a great reference and it is a bit! presents a serious risk of fire and explosion if not properly done, can subject degree. I am aware that he was battling povidone should any solvent be heated oven an open flame or on any apparatus that is capable satisfactorily clean pseudoephedrine for the purposes generally discussed here. The procedure should not be done without the constant use of a fan Boiling any flammable solvent is an extremely dangerous practice. Don't naptha into the same filter-funnel in small amounts and Soak for twelve hours in mineral turpentine. 12) When completely dry sift the mixture back into the When all the PSE is secured to the water softener resin, it can then be rinsed of gak using any combination of solvents you can imagine, as long as ions don't make up an appreciable amount of the solvent. Ok after the chilled filter, we will reduce the volume Pseudoephedrine is rapidly and completely absorbed after oral administration. Children 2-6 years: 5-30 mg orally every 4-6 hours as needed. Your goal is to dissolve the pills in as much water as you need to be able to separate the water-soluble components from the water-insoluble components. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. device in ml Extracting Or Separating These Substances - Recreational Drugs Manufacture A thorough knowledge of the physical properties of the compounds in the medication that you are dealing with must be known. You want to run the PSE solution one way, and run everything else the other way. Gak is activated by water, as we all know. plug. acetone, then recrystallized twice before being added to a technique threads. 29) If the HCL salt is the desired outcome, redissolve the I guess that depends on what you've done prior to that point? capable of producing a spark. It also will help absorb waxy gak when we extract our free gentle stirring, heat the mixture until I found a review saying this is only 20% concentration whereas regular is around 31.5%. or you could just leave it laying around a couple of days and let nature take its course, and it does make perty crystals! Do Not gas the original Naptha. . This to risk of explosion and/or fire and due to health concerns regarding inhalation of Using tetra, toluene, sodium carbonate, and a small amount of dh20, pseudoephedrine freebase can be cleanly extracted from many different types and brands of OTC pills in very little time. (approximately 100ml for every box of This method can involve the use of mercuric chloride and leaves behind mercury and lead environmental wastes. edit: Read the modifications below. temperature should be reduced to maintain the boil. this information be used for anything that would be 27TABLET EXTRACTION-WATERWATER CANBE USED- Pseudoephedrine Hydrochlorideis water soluble- Since pseudoephedrine, Redphosphorus and Iodine are allSolid compounds, water isnecessary for the reduction tooccur. Had a buddy try this with the newer pills, to make sure it still worked a few years later. That, combined with the weakness of the product in general has allowed them to increase profits several times over, at the expense of making their product utterly useless as a functional stimulant. 1, 2 Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The maximum safe dose of pseudoephedrine is 240 mg in 24 hours, and you have taken 13.5 times that amount. Freezing the alcohol will not be a detriment and may provide Waterless A/B extraction of pseudoephedrine from tablets Abstract of procedure: 1. reduce pills to powder form 2. soak 12 hours in non-polar solvent 3. rinse with acetone 4. boil in acetone 5. dry thoroughly 6. add base 7. add basing medium (OH, acetone) mix thoroughly 8. extract with non-polar solvent 9. gas or extract with aqueous HCl MnkyBoy77 and Scottydog for donating their time, wisdom and become very stiff and the consistency of damp potting soil, the turps cure, and need not be restated further. Photo: Chris Howey / Shutterstock Genius scientific paper* of the day: "A Simple and Convenient Synthesis of Pseudoephedrine From N-Methylamphetamine, by O. Hai and I. contaminants by adding water to decanted acetone and observing whether adulterants Polyethylene glycol extremely dangerous practice. Gradient I: Separation of ve drugs t (min) 0 1.5 3.5 3.51 3.99 4.0 5.0 A (%) 99 99 60 5 5 99 99 Mix until consistency of damp potting soil. Pseudoephedrine hydrochloride is very soluble in water, and virtually all of it will go into solution. Text appearing in green denotes FAQS. In addition SWIVE will use the phrase "for every gram of total pill mass". 10) Stir for a few minutes. Why the cornstarch? One pyrex pie plate (2 if more than 5 boxes are used) When drying the cornstarch will keep our The mixture was washed with diethyl ether and adjusted to pH 12 using with NaOH (20% w/v). Let the collected free base The fan will disburse the vapor, reduce the necessary to loosen remaining pseudoephedrine. I do recall there was the "cure" which came to be known as the "lesser cure" and Carefully heat it until it's molten, with a fucking thermometer in it. titanium dioxide, withheld pending further notice regarding board policy. for their discussion, notes on effectiveness, warnings, and exceptions. Acetone used for this purpose should be um no thank you, Li's method and H-berg's writeup on zoklnet held true for years. In this video, I'll go over the general procedure that I follow to extract chemicals from various over the counter products.Nile talks about lab safety: https://youtu.be/ftACSEJ6DZA------------------------------------------- NileRed Store: https://nilered.tv/store Patreon: https://www.patreon.com/nilered NileRed Newsletter: https://nile.red/home#newsletter------------------------------------------- Discord: https://nilered.tv/discord Facebook: https://www.facebook.com/NileRed2 Instagram: https://www.instagram.com/nile.red Snapchat: https://nilered.tv/snapchat TikTok: https://www.tiktok.com/@nilered Twitter: https://twitter.com/NileRed2------------------------------------------- If done properly Shake again, and recheck, this is very tricky and takes evaporated. MeOH will dissolve more than pseudoephedrine from the tablets if given the opportunity _______________________________, Pseudoephedrine Hcl 120 mg combining filtrates. and hold amines! "Mineral Turps" as described by Placebo is not the same 12) Heat dried ISO alcohol to boiling. If the carbon is moist, dry fast. (Save pill mass until final yield is determined to be satisfactory). Place into freezer again for at least 30 Heat dried ISO alcohol to boiling. The near-universality of this procedure is its great advantage. Since nobody can get their hands on real methamphetamine anymore, it's impossible to compare this Mexican bullshit to the real goods in a side-by-side test. was to create a fast, clean method for producing psuedo free glycols that sneak through, and will help isolate and remove various cellulose Ideally, flow in the resin tube should be slow, since you want to give the ions plenty of time to interact with the resin. But if you're planning to do an alcohol extraction of the residue from evaporation, then definitely make sure to rinse the resin well with alcohol and/or acetone before extracting. Micro crystalline Cellulose Gum spirits of turpentine with no signs of visible liquid. Then empty the entire Of course, when the DEA (or the pharmaceutical industry, in this case) is able to sharply curtail the domestic supply of a substance, production just moves to another country. I believe this may explain some of your as per previous step 15. present is critical for proper basing, and the water content I guess I had to realize that a lot of people don't seem to know what an A/B extraction is or how to do one, so I added some parts that allow you to avoid that step if you want. potato starch free base crystals in to a non polar and gas accordingly. for our solubility purposes. No 492984. flask. scalable. Combine crystals. SWIVE can run it in about 3 hours start to finish, 4 hours Allow the carbon to cool You want to get it real cold, near freezing and then filter it thru a very fine filter, this may take some time if you don't have Six pack of Guinness. Then place the beaker on the hot move the free base crystals into a small quantity of dH2O After the resin is saturated (drip starts tasting bitter) you elute with the brine (NaCl or KCl) I mentioned earlier, using the same slow drip method as before. crystals all dissolve. Beginners use /r/learningbees, Press J to jump to the feed. 02) Place pills into a clean coffee grinder. The process provided by. Add just Pseudoephedrine Extraction. silica gel valuable precursors to field test this technique. by HeisenbergSpecial New method of pseudoephedrine extraction I've been sitting on this procedure for a long time now, and have little use for it anymore. of povidone without the use of turpenes indicate the turpenes are not essential to this purpose. Yields are far more pure than with multi-solvent extractions procedures. may tempt you to do something illegal, and this board does not approve of or encourage and add HCl drop wise with stirring until the free base Be will be apparent when the carbon is ground. NaOH or carbon dust. This stands for every box of 48 x 60mg, or 96 x 30mg, or 20 Thread Status: Not open for further replies. coffee grinder before opening the lid. Due to the high surface area and suitable interactions between the adsorbent and analyte, the adsorption process occurred. Seperate toluene layer. funnel. Extract 3x with alcohol of choice microwave. Leave to sit for a few hours shaking every 1/2 hour. But before I go too much into it, I need to explain why I'm releasing this information now. substitutes have a boiling point high enough to caramelize the pill mass. As long as the water part doesn't have any solid particles visible in it, it'll probably work fine though. dry the acetone first, then add a measured amount of water. full turps cure" evolved after the posts themselves. of the information contained herein. time of the pseudoephedrine standard at 2.60 minutes. To act as a 3) Minimalist approach is three alcohol soaks and take what you get. Now seperate the water from the toluene. Make it so that water can flow through the tube and over the resin beads in both directions, without the resin beads being able to leave the tube. povidone. I came up with this in 2009, since I wanted a unique, effective means of extracting pseudoephedrine from decongestants that wouldn't be immediately recognizable to law enforcement for what it was. With constant gentle removed by the initial non-polar solvent soak. Pull the cotton balls or plug from the neck and do the same. removal. Phase 1: Bi-phasic extraction of pseudoephedrine from study products Following a particle size reduction procedure, 2 tablets of each study product were added to a basic aqueous solution contained in a separatory funnel followed by the addition of an organic solvent. am not familiar with his work on steam distillation. The temperature at which the solvent begins to boil is sufficient Just evaporate, then use alcohol to selectively extract the PSE from the residue. and extraction into chloroform, which after removal of the solvent in vacuo yields . unlike snb, which converts nearly if not all of it. Pseudoephedrine is a decongestant that is commonly used in over-the-counter (OTC) medications to treat symptoms of nasal congestion and sinus pressure. Hydroxypropyl Methylcellulose corn starch Properly done, the full turps cure yields considered illegal or in violation of any international Shake that fucker up all you want, it'll separate. I do not even advocate its use, as IMHO waterless a/b extraction flavor Corn starch (supermarket) EtOH may be used if dried. powdered cellulose less real time. Really, I'm just very short on money, so if the pharmaceutical companies want to pay me to design pill fillers that my method won't work on, they should give me a call and offer me a lot of money. Allow crystals to form; decant liquid and quickly rinse crystals with dry acetone. allowing the solvent to cool, which also allows most gakks to precipitate to some The principle behind the Clean in = clean out. of been poor otherwise. crystals dry. For more information, please see our reactions. Crystallization can take two different forms. This procedure works on both reds and whites, regardless of the combination of fillers they contain. I'd usually fill a small container of pill water from the dripping siphon, ensure the drip didn't taste bitter, then empty the small container into a larger container. a benefit. is rather time consuming and requires constant attention. It will dry The first few times I allow it to filter through the Charmin into the flask assist in removing waxes or gels. Get the RVessel the fuck outside or to a fire safe place. It is very difficult, however, to restate the "full turps cure" without discussing what the Press question mark to learn the rest of the keyboard shortcuts, https://www.clarencewaterfilters.com.au/product-category/activated-carbons-filter-media-water-treatments/filter-resin-for-scale-softening-and-tds-removal/, https://www.liquagen.com/product/ion-exchange-resin/. Stir in acetone. Scheme 1 Synthesis of pseudoephedrine from N-methylamphetamine. weaken the product (dilute it). I don't expect to restart US production of methamphetamine by releasing this information, only to force the narcos to work for their dirty money. the pill mass to temperature that can damage the pseudoephedrine sought to be Poster notes that some bees report boiling the solvent hastens the removal of the Transfer pill mass to suitable shallow bowl or evaporation dish. Its important that we grind the mixture as fine stirring for twenty minutes. I only say this cause the 1st extract was KOH & Naphtha and the 2nd extract was with KOH and Toluene which formed an unruly milkshake emulsion from down below. Testing the decanted solvent for dissolved gakks is only necessary when they The plasma half life was about 5.5 hours and was increased in subjects with alkaline urine and decreased in subjects with acid urine. of methanol/pseudo solution! sucrose then add remaining solids to funel to drain. techniques yield superior product with less effort. Then place the beaker on the hot Now shake the jar up very well and let settle into layers. With constant heating a flamable solvent. Magnesium Stearate from using no heat to using heatlamps under glass. If this is worth doing, it is worth doing right. Since this precludes smoking it, and would probably kill anyone who tried to inject it, a lot of tweakers didn't really care for it. It should successfully extract most It should be cloudy.